• Orifex 120 mg/180 mg
  • Dosage Form: Tablets
  • Pack Type: Blister
  • Pack Size: 10*10
  • Division: Unimax

ORIFEX 120/180

Fexofenadine 120/180

ORIFEX 120: Each film-coated tablet contains fexofenadine 120mg.

ORIFEX 180:Each film-coated tablet contains fexofenadine 180 mg.

Clinical Pharmacology:

Fexofenadine is a second generation antihistamine. It is a peripheral histamine H1 receptor antagonist that binds to and block the H1 receptors preventing histamine from

binding to these receptors and thus blocking the allergic reaction.

It is mainly used to treat allergic conditions like allergic rhinitis (hay fever) and chronic urticaria (hives).

The usual dose for treating hay fever is:

120mg once a day for adults and children aged 12 years and over.

The usual dose for treating hives is:

180mg once a day for adults and children aged 12 years and over.

-Coadministration of fexofenadine hydrochloride with erythromycin or ketoconazole may result in  increase in the level of fexofenadine in plasma. 

-The administration of an antacid containing aluminium and magnesium hydroxide gels may reduce the bioavailability of fexofenadine, most likely due to binding in the gastrointestinal tract. It is advisable to leave 2 hours between administration of fexofenadine hydrochloride and aluminium and magnesium hydroxide containing antacids.

Tell your doctor immediately and stop taking Fexofenadine Tablets if you experience: -

swelling of the face, lips, tongue or throat, flushing, chest tightness and difficulty breathing, as these may be signs of a serious allergic reaction

The Common side effects include: -



feeling sick (nausea)


Warnings and precautions

Talk to your doctor before taking Fexofenadine Tablets if you:

-have problems with your liver or kidneys

-have or ever had heart disease



Category C

There are no adequate and well controlled studies in pregnant women. Fexofenadine hydrochloride should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.