Information

  • Silorex 4mg/8mg
  • Dosage Form: CAPSULES
  • Pack Type: STRIP
  • Pack Size: 1*10's
  • Division: Unitus

SILOREX- 4/8

Silodosin 4mg, 8mg

SILOREX 4: Each hard gelatin capsule contains Silodosin 4 mg.

SILOREX 8: Each hard gelatin capsule contains Silodosin 8 mg.

 

Clinical Pharmacology:

         Silodosin selectively blocks the alpha- 1A receptors, which is found in the prostrate gland, bladder neck and urethra. By blocking these receptors, it relaxes the smooth muscles in theses areas, which helps improve urine flow and reduces benign prostatic hyperplasia (BPH)  symptoms.
 

 

 

Silodosin is used to treat signs and symptoms of an enlarged prostate gland in men,  known as benign enlargement of the prostate (benign prostatic hyperplasia or BPH)  which includes difficulty urinating, painful urination, urinary frequency and urgency.

Take Silorex only as directed by your doctor.

It is best to take Silorex with meal at the same time every day. Do not crush or chew this medication; Swallow the capsule whole, preferably with a glass of water.

The dosage is based on your medical condition and response to treatment. The usual adult dose is 8 mg once a day for BPH.

Missed dose

If you miss a dose of Silorex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

 

 

 

 

 

 

Silorex can interact with other medications, vitamins or herbs you may be taking.Talk with your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

Tell your doctor beforehand, in particular, if you take:

  • medicines which lower blood pressure as there may be the potential risk that the effect of these medicines is increased whilst taking Silorex.
  • antifungal medicines (such as ketoconazole or itraconazole) can increase the level of Silorex in blood.
  • medicines used for HIV-AIDS (such as ritonavir) or medicines used after transplants to prevent organ rejection (such as cyclosporin) because these medicines can increase the blood concentration of Silorex
  • medicines for epilepsy or rifampicin (a medicine to treat tubercolosis), since the effect of Silorex may be reduced.
  • antibiotics such as clarithromycin and erthromycin may increase the level of Silorex in blood and increase the risk of side eefcts.
  • other drugs used to treat BPH increases the risk of hypotension and orthostatic hypotension.
  • drugs used to treat erectile dysfunction may also cause hypotension.

Contact your doctor immediately if you notice any of the following allergic reactions: swelling of the face or throat, difficulty in breathing, feeling faint, itchy skin or hives.

Silodosin may cause dizziness or faintng, especially when you first start  taking it.You may feel very dizzy when you get up too fast from a sitting or lying position.If you do feel weak or dizzy, make sure you sit or lie down straight away until the symptoms have disappeared. In case these symptoms are severe, please inform your doctor as soon as possible.

The common side effect with silodosin is a decrease in the amount of semen during intercourse (due to retrogade ejaculation). This effect disappears after discontinuation of Silodyx. Please inform your doctor if you are planning to have children.

Other mild common side effects include: diarrhea, headache, common cold, stuffy nose. These side effects may disappear within few days or coule of weeks. Talk to your doctor if they are more severe or don't go away. 

Some side effects can be serious. If you experience any of these symptoms, call your doctor immeditely:

  • yellowing of the skin or the whites of your eye, nausea, vomitting, loss of appetite, stomach pain and swelling, bruising easily, pale stool color, dark urine, unusual or unexplained tiredness
  • painful erection of the penis that lasts for several hours

 

Silodosin may cause complications during a cataract surgery. It is important that you immediately inform your eye specialist if you are using or have previously used Silodosin.

As it may cause orthostatic hypotension, which may lead to dizziness and fainting, do not drive, operate machinery and perform hazardous tasks until you know how this medication affects you.